This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartila…
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization an…
Acts as a acyl-protein thioesterase (PubMed: 19439193, PubMed: 20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimer…
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed: 10434065, PubMed: 12616642). Capable …
Lipid-modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid comp…
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate …
Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response recept…
