Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to ce…
Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEP…
Receptor for hormone LEP/leptin (Probable) (PubMed: 11861497). On ligand binding, mediates LEP central and peripheral effects through the activation of diffe…
LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal an…
The Insulin-like growth factors possess growth-promoting activity (PubMed: 29440408). Major fetal growth hormone in mammals. Plays a key role in regulating f…
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 r…
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells…
Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins.…
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which …
