Sphingosine 1‐phosphate (SPP) is an important sphingolipid‐derived second messenger in mammalian cells that acts to promote proliferation and to inhibit apop…
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentr…
Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stim…
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stim…
Pentosidine is an advanced glycation end product (AGE) and cross-linked substance with fluorescent properties. Pentosidine is present in various human tissue…
ProBDNF is the precursor of mature BDNF. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the periphera…
