Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radic…
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and
Caspase-3 is a cytoplasmic cysteine protease involved in the activation cascade of caspases responsible for execution of apoptosis. At the onset of apoptosis…
Adenosine 3’,5’-cyclic monophosphate (cyclic AMP, cAMP) is an important “second messenger” involved in many physiological processes. It plays a key role as a…
Calprotectin(S100A9) is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It …
Bcl-2 is the founding member of the apoptotic-regulating Bcl-2 family of proteins. It is considered an apoptosis suppressor in many cell systems and has been…
Bax is a pro-apoptotic factor of Bcl-2 family. It accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adeno…
