Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development (By similarity). Binds iron through associat…
Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi
Forms a Channel that mediates water and glycerol transport across cell membranes at neutral pH (PubMed: 9252401). The Channel is also permeable to urea (PubM…
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription …
Plays a role in the cellular breakdown of insulin, APP Peptides, IAPP Peptides, natriuretic Peptides, glucagon, bradykinin, kallidin, and other Peptides, and…
