It is a group of metabolites of cholesterol in the liver decomposition and enteric-liver circulation, and is the final product of cholesterol catabolism in t…
Sphingosine 1‐phosphate (SPP) is an important sphingolipid‐derived second messenger in mammalian cells that acts to promote proliferation and to inhibit apop…
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stim…
Prostaglandin E2 (PGE2) is an extensively studied prostaglandin owing to its predominance in inflammation, cancer, atherosclerosis, autoimmune disease, and s…
Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls. For instance, may …
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's proc…
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal…
