Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates…
Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex…
Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8 (Pub…
G protein-coupled receptor for follitropin, the follicle-stimulating hormone (PubMed: 11847099, PubMed: 24058690, PubMed: 24692546). Through cAMP production …
A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins (PubMed: 2732228, PubMed: 10681376, PubMed: 11093772, PubMed: 128…
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed: 15283675, PubMed: 8168535). Biologically impo…
Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled ge…
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring withi…
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power s…
Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine…
