Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to
Plays a central role in autophagy (PubMed: 10604474, PubMed: 12372286, PubMed: 19270693, PubMed: 28445460). Acts as core subunit of different PI3K complex fo…
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimu…
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mi…
The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin
Cleaves aggrecan, a cartilage proteoglycan, at the '1691-Glu-|-Leu-1692' site (within the chondroitin sulfate attachment domain), and may be involved in its …
Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism (PubMed: 11788823, PubMed: 12671033). Proposed to play a role