Plays a critical role in MHC class II antigen processing by stabilizing Peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis…
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked t…
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of…
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome (Pub…
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but …
Protein kinase involved in the regulation of transcription (PubMed: 10574912, PubMed: 10757782, PubMed: 11145967, PubMed: 11575923, PubMed: 11809800, PubMed:…
Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-ce…
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lecti…
Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.…
A positive regulator of the alternate pathway (AP) of complement (PubMed: 20382442, PubMed: 28264884). It binds to and stabilizes the C3- and C5-convertase e…
