Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal …
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellul…
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting prolif…
Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome b…
[Isoform 1]: Water Channel that mediates water transport across cell membranes irrespective of the cytosolic pH (PubMed: 1208$458.00|$300.001, PubMed: 217338…
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate (PubMed: 11956206, PubMed: 16269826, PubMed: 19168031). Acts efficiently …
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrec…
Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-…