Forms a water-specific Channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permittin…
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB…
Water Channel required to promote glycerol permeability and water transport across cell membranes (PubMed: 12239222, PubMed: 30420639). Acts as a glycerol tr…
Forms a water-specific Channel (PubMed: 7559426, PubMed: 8601457, PubMed: 19383790). Plays an important role in brain water homeostasis and in glymphatic sol…
Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Plays a critical for normal cellular functions such as general prot…
Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7),…
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mi…
Antigen-presenting major histocompatibility complex class I (MHCI) molecule with an important role in reproduction and antiviral immunity (PubMed: 20972337, …
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses (PubMed: 15226432, PubMed: 15509808, PubMe…
Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, …
