Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds th…
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) an…
Lysosomal serine protease with tripeptidyl-peptidase I activity (PubMed: 11054422, PubMed: 19038966, PubMed: 19038967). May act as a non-specific lysosomal p…
Photoreceptor required for image-forming vision at low light intensity (PubMed: 8107847, PubMed: 7846071). Required for photoreceptor cell viability after bi…
Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absenc…
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play
Component of a protein kinase signal transduction cascade (PubMed: 9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K…