Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtrat…
NAD(P)H-dependent oxidoreductase involved in metabolic inactivation of pro- and anti-inflammatory eicosanoids: prostaglandins (PG), leukotrienes (LT) and lip…
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storag…
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storag…
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins…
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second me…
Inward rectifier potassium Channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium Channels are characterized by a greater tendency to…
In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium Channels are characterized by a greater tendency to allow pot…
pH-dependent, voltage-insensitive, background potassium Channel protein. Rectification direction results from potassium ion concentration on either side of t…
