Calcium-permeable, non-selective cation Channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head …
Ligand-activated non-selective calcium permeant cation Channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx …
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to ty…
Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstr…
Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic aci…
Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their …
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed: 7980644, PubMed: 9169443, PubMed: 9490062, PubMed: 1…
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol (PubMed: 16647063, PubMed: 11294643). Plays a …
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol (PubMed: 16154994, PubMed: 16647063, PubMed: 9…