Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhe…
Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds th…
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) an…
Lysosomal serine protease with tripeptidyl-peptidase I activity (PubMed: 11054422, PubMed: 19038966, PubMed: 19038967). May act as a non-specific lysosomal p…
Photoreceptor required for image-forming vision at low light intensity (PubMed: 8107847, PubMed: 7846071). Required for photoreceptor cell viability after bi…
Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absenc…
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play