Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex n…
Chemoattractant for eosinophils and basophils (PubMed: 10415065, PubMed: 10488147). Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mo…
Dipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4). Does not hydrolyze cystinyl-bis-glycine. Independently of its dipeptidase activ…
Cleaves and degrades bioactive Peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (PubMed: 3233187, PubMed: 1515063). Also cleaves Arg-Arg-be…
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regener…
Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by th…
Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by
A cytochrome P450 monooxygenase involved in the metabolism of endocannabinoids and steroids (PubMed: 21289075, PubMed: 12865317). Mechanistically, uses molec…
