Regulates cellular transport and efflux of cholesterol (PubMed: 26941018). Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal me…
Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes (PubMed: 16143324). Can bind to the ER membrane pro…
Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine wit…
Chemoattractant active on T-lymphocytes and monocytes but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise …
Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate, with a particular r…
A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrog…
Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytoc…
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exoso…
Tachykinins are active Peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indire…
