Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably th…
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal …
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting prolif…
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellul…
Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome b…
[Isoform 1]: Water Channel that mediates water transport across cell membranes irrespective of the cytosolic pH (PubMed: 1208$458.00|$300.001, PubMed: 217338…
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate (PubMed: 11956206, PubMed: 16269826, PubMed: 19168031). Acts efficiently …
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrec…
