Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usu…
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation…
Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-depen…
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and oth…
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium Channel complex of pore-forming alpha subunits. Modulates the gating kineti…
Voltage-gated potassium Channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain. Mediates the major part of th…
Potassium Channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (PubMed: 10646604, PubMed: 25441029). As…
Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probab…
