Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a Peptide stretch, called the 'bait region' which
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC si…
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartila…
Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading t…
Plays a role in lysosome motility (PubMed: 16537643, PubMed: 25898167). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysos…
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization an…
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play …
Acts as a acyl-protein thioesterase (PubMed: 19439193, PubMed: 20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimer…
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed: 11772874). Capable of activating medi…
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed: 10434065, PubMed: 12616642). Capable …