Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium Channel activity. Promotes neuronal excitabi…
Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:
Plays a central role in cell adhesion in hematopoietic cells (PubMed: 19234463, PubMed: 26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and…
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z…
B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required f…
Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (PubMed: 12500905, PubMed: 23435…
Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within s…
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogen…