May play a role in cell differentiation, proliferation and apoptosis (PubMed: 24556617). Binds cholesterol in cholesterol-containing plasma membrane microdom…
Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (PubMed: 18487197). Contributes to proline 3-hydroxylat…
May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SC…
Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction in…
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it a…
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essent…
Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. C-terminal processed part of PCPE (CT-PCPE) may have…
Pseudouridine Synthase that catalyzes pseudouridylation of mRNAs (PubMed: 28073919). Mediates pseudouridylation of mRNAs with the consensus sequence 5'-GUUCN…