Endoribonuclease that cleaves tRNAs and rRNAs (PubMed: 29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed: 29563550). …
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytos…
May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in…
Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes T…
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors (PubMed: 29769720). Upon binding to LGR4-6 (LGR4, LGR5 or LGR6),
Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral mi…
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endot…
Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium Channel KCNH2/HERG, or by assisting its synthesis, foldin…
