Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/pha…
Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed: 20215400). Required for actin polymerization at immunol…
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form a…
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory …
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types …
Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the s…
G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed: 1330647, PubMed: 18703043, PubMed: 19057895). Also functions as a receptor for variou…
