In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor a…
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed: 11809832). In conjunction with the subcortical maternal complex (SCMC), p…
Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins (By simil…
Major secreted protease of mast cells with suspected roles in vasoactive Peptide generation, extracellular matrix degradation, and regulation of gland secret…
Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells
Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhi…
Can insert into membranes and form chloride ion Channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur on…
