Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed: 10688651, Pu…
Forms a water-specific Channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move …
Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth…
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that pro…
Transcriptional activator that recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' and regulates different processes, such as apoptosis and autophag…
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress (PubMed: 10358076, PubM…
Forms a water-specific Channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permittin…
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB…
Water Channel required to promote glycerol permeability and water transport across cell membranes (PubMed: 12239222, PubMed: 30420639). Acts as a glycerol tr…
Forms a water-specific Channel (PubMed: 7559426, PubMed: 8601457, PubMed: 19383790). Plays an important role in brain water homeostasis and in glymphatic sol…
