F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subuni…
May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity
Binds to actin filaments in muscle and non-muscle cells (PubMed: 23170982). Plays a central role, in association with the troponin complex, in the calcium de…
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one stra…
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing…
Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (PubMed: 8146186, PubMed: 8048929, PubMed: 23408426). Its binding with CCL2 on monocytes an…
Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed: 17177976, PubMed: 18172500, PubMed: 1…
Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and ma…
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic developme…
