Major secreted protease of mast cells with suspected roles in vasoactive Peptide generation, extracellular matrix degradation, and regulation of gland secret…
Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells
Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhi…
Can insert into membranes and form chloride ion Channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur on…
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to
Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the matching and maintenance of pre- and post-syna…
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but …
Key functional receptor for CCL2 but can also bind CCL7 and CCL12 chemokines (PubMed: 8631787, PubMed: 8662823, PubMed: 8996246). Its binding with CCL2 on mo…