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Background
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Product overview
Product Name
Tyrosine-protein phosphatase non-receptor type 6
Code
E2310Ra
Assay type
Sandwich
Size
96 test
Sensitivity
9.14ng/L
Reactivity
Rat
Detection range
9.14ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Protein-tyrosine phosphatase SHP-1;Ptph6;PTPN6;Shp-1;Tyrosine-protein phosphatase non-receptor type 6
