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Background
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (By similarity). May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
Product overview
Product Name
Topoisomerase 2
Code
E1314Ra
Assay type
Sandwich
Size
96 test
Sensitivity
0.11ng/ml
Reactivity
Rat
Detection range
0.11ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
DNA topoisomerase 2-alpha;DNA topoisomerase II, alpha isozyme;TOP 2A;TOP2A