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Background
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis (By similarity). May also act as a regulator of adult uterine morphology and function (PubMed: 12063187). May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (PubMed: 12960062). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (By similarity).
Product overview
Product Name
Secreted Frizzled Related Protein 4
Code
E1143Ra
Assay type
Sandwich
Size
96 test
Sensitivity
0.025ng/ml
Reactivity
Rat
Detection range
0.025ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
DDC-4 protein;Secreted frizzled-related protein 4;SFRP 4;SFRP4;sFRP-4
