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Background
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake.
Product overview
Product Name
Erythroferrone
Code
E2446Ra
Assay type
Sandwich
Size
96 test
Sensitivity
10.49ng/L
Reactivity
Rat
Detection range
10.49ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Complement C1q tumor necrosis factor-related protein 15;ERFE;Erythroferrone;Fam132b;Myonectin