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Background
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG5 has ATPase activity.
Product overview
Product Name
ATP-binding cassette sub-family G member 8
Code
E1247Ra
Assay type
Sandwich
Size
96 test
Sensitivity
10.21ng/L
Reactivity
Rat
Detection range
10.21ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
ABCG8;ATP-binding cassette sub-family G member 8;Sterolin-2
