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Background
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity.
Product overview
Product Name
Atp-Binding Cassette Sub-Family G Member 5
Code
E1246Ra
Assay type
Sandwich
Size
96 test
Sensitivity
7.21ng/L
Reactivity
Rat
Detection range
7.21ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
ABCG 5;ABCG5;ATP-binding cassette sub-family G member 5;Sterolin-1
