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Background
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity).
Product overview
Product Name
Interleukin-23 Receptor
Code
E2185Mo
Assay type
Sandwich
Size
96 test
Sensitivity
9.91ng/L
Reactivity
Mouse
Detection range
9.91ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
IL 23R;IL-23 receptor;IL23R;IL-23R;Interleukin-23 receptor