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Background
Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis.
Product overview
Product Name
Integrin Alpha-2B
Code
E2153Mo
Assay type
Sandwich
Size
96 test
Sensitivity
0.024ng/mL
Reactivity
Mouse
Detection range
0.024ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD49b;CD49 antigen-like family member B;Collagen receptor;GPIa;Integrin alpha-2;ITGA 2;ITGA2;Platelet membrane glycoprotein Ia;VLA-2 subunit alpha;
