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Background
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores (PubMed: 24880340). Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake (PubMed: 22351773).
Product overview
Product Name
Erythroferrone
Code
E2681Mo
Assay type
Sandwich
Size
96 test
Sensitivity
10.14ng/L
Reactivity
Mouse
Detection range
10.14ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Complement C1q tumor necrosis factor-related protein 15;ERFE;Erythroferrone;Myonectin