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Background
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes.
Product overview
Product Name
Cytochrome b-245 heavy chain
Code
E1992Mo
Assay type
Sandwich
Size
96 test
Sensitivity
9.75ng/L
Reactivity
Mouse
Detection range
9.75ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
C88302;Cgd;CGD91-phox;CYBB;Cyd;Cytochrome b(558 subunit beta;Cytochrome b-245 heavy chain;Cytochrome b558 subunit beta;gp91<ph;gp91-1;gp91p;gp91phox;gp91-phox;Heme-binding membrane glycoprotein gp91phox;Neutrophil cytochrome b 91 kDa polypeptide;No;Nox2;p22 phagocyte B-cytochrome
