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Mouse Bone Morphogenetic Protein Receptor Type-1B, BMPR1B ELISA Kit

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BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1. Receptor for GDF5 (PubMed: 26105076, PubMed: 19229295). Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed: 24098149).

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