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Background
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Product overview
Product Name
USP6 N-Terminal Like Protein
Code
E2339Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.35ng/L
Reactivity
Human
Detection range
9.35ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Related to the N-terminus of tre;RNTRE;RN-tre;TRE2NL;USP6 N-terminal-like protein;USP6NL;USP6NL-IT1