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Background
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
Product overview
Product Name
Suppressor of cytokine signaling 6
Code
E6234Hu
Assay type
Sandwich
Size
96 test
Sensitivity
4.84ng/L
Reactivity
Human
Detection range
4.84ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CIS4;CIS-4;Cytokine-inducible SH2 protein 4;HSPC060;SOCS4;SOCS-4;SOCS6;SOCS-6;SSI4;STAI4;STATI4;Suppressor of cytokine signaling 4;Suppressor of cytokine signaling 6;
