BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.
Background
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed: 15601820, PubMed: 21199876). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed: 21199876). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed: 21199876).
Product overview
Product Name
Spry Domain-Containing Socs Box Protein 1
Code
E3178Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.96ng/L
Reactivity
Human
Detection range
9.96ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
SPRY domain-containing SOCS box protein 1;SPSB 1;SPSB1;SSB-1
