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Background
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.
Product overview
Product Name
SPARC
Code
E6206Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.48ng/mL
Reactivity
Human
Detection range
9.48ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
Basement-membrane protein 40;BM-40;OI17;ON;ONT;Osteonectin;Secreted protein acidic and rich in cysteine;SPARC
