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Background
Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
Product overview
Product Name
Signal Peptide, Cub and EGF-like Domain-Containing Protein 3
Code
E4518Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.021ng/ml
Reactivity
Human
Detection range
0.021ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
SCUBE 3;SCUBE3;Signal Peptide, CUB and EGF-like domain-containing protein 3