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Background
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT (PubMed:15525651).
Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis (PubMed:16580887).
Product overview
Product Name
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Code
E6152Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.02ng/L
Reactivity
Human
Detection range
9.02ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Medium tumor antigen-associated 61 kDa protein;MRD36;PP2A subunit A isoform PR65-alpha;PP2A subunit A isoform R1-alpha;PP2AA;PP2AAALPHA;PP2A-Aalpha;PPP2R1A;PR65A;Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
