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Background
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.
Product overview
Product Name
Serine/Threonine-Protein Kinase Nek3
Code
E3202Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.024ng/ml
Reactivity
Human
Detection range
0.024ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
HSPK 36;NEK 3;NEK3;Never in mitosis A-related kinase 3;NimA-related protein kinase 3;Serine/threonine-protein kinase Nek3
