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Background
Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Product overview
Product Name
RNA-binding protein EWS
Code
E6103Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.57ng/L
Reactivity
Human
Detection range
7.57ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
bK984G1.4;Ewing sarcoma breakpoint region 1 protein;EWS;EWS oncogene;EWS-FLI1;EWSR1;RNA-binding protein EWS
