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Background
Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5′-ATT-3′ reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending.
Product overview
Product Name
Replication Initiator 1
Code
E2401Hu
Assay type
Sandwich
Size
96 test
Sensitivity
10.48ng/L
Reactivity
Human
Detection range
10.48ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
60 kDa origin-specific DNA-binding protein;60 kDa replication initiation region protein;ATT-binding protein;DHFR oribeta-binding protein RIP60;REPIN 1;REPIN1;Replication initiator 1;Zinc finger protein 464
