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Background
GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
Product overview
Product Name
Ras-Related Protein Rap-1B
Code
E6065Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.53ng/L
Reactivity
Human
Detection range
9.53ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
GTP-binding protein smg p21B;RAP 1B;RAP1B;Ras-related protein Rap-1b