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Background
May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
Product overview
Product Name
PTB domain-containing engulfment adapter protein 1
Code
E6039Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.17ng/L
Reactivity
Human
Detection range
7.17ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CED6;CED-6;Cell death protein 6 homolog;GULP;GULP1;Protein GULP;PTB domain adapter protein CED-6;PTB domain-containing engulfment adapter protein 1